4 Biotech Stocks That Could Be Bargains

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Biotech stocks person had an uneven 2021 truthful far.

One large biotech fund, the iShares Biotechnology exchange-traded money (ticker: IBB), which focuses connected the bigger biotech players, is up 9%, conscionable down the S&P 500 index, which is up 14.3%. Another important fund, the SPDR S&P Biotech ETF (XBI), which spreads its assets crossed ample and tiny biotech firms, is down 8.9% implicit the aforesaid period.

The occurrence of biotech standouts astatine processing Covid-19 vaccines astatine a accelerated gait has drawn caller attraction and investors to the sector, and a illustration of wellness care/biotech-dedicated funds tracked by Piper Sandler expert Christopher Raymond has seen $1.3 cardinal successful inflows truthful acold this year.

Picking the adjacent large biotech stock, however, is tricky, and requires a extent of specialized knowledge. The champion proposal is mostly to fto the specialists astatine biotech-and-health-care-focused ETFs and communal funds bash the enactment for you.

For those who privation to marque a prime connected their own, 1 strategy is to hunt for worth by looking for biotech stocks that commercialized astatine the steepest discount to wherever Wall Street analysts expect them to commercialized successful the adjacent term.

Company / TickerRecent PriceAverage Target PriceImplied Gain
TG Therapeutics / TGTX$37.32$75.88103.3%
Vir Biotechnology / VIR$37.91$74.2996.0%
Ultragenyx Pharmaceutical / RARE$85.49$153.1279.1%
Exelixis / EXEL$16.67$29.5477.2%

Source: FactSet

Analysts people people prices for the stocks they cover, a terms they expect the banal to deed astatine immoderate constituent successful the future, usually astir a twelvemonth out. Last month, we looked astatine the 5 health-care stocks successful the S&P 500 that commercialized the farthest beneath their mean expert price targets.

This time, we’ve looked astatine the stocks successful the SPDR S&P Biotech and the iShares Biotechnology ETFs with marketplace values of implicit $5 billion, and we recovered the 4 that commercialized the farthest beneath their mean people prices, according to FactSet.


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We acceptable the $5 cardinal marketplace worth arsenic a level to exclude immoderate smaller stocks with conscionable a mates of analysts covering them, for which mean expert people prices don’t mean much.

The stocks that passed the surface are TG Therapeutics (TGTX), Vir Biotechnology (VIR), Ultragenyx Pharmaceutical (RARE), and Exelixis (EXEL), a radical of absorbing biotech stocks backed by important Wall Street expert enthusiasm.

The banal successful the radical that trades the farthest beneath its mean expert people terms is TG Therapeutics, a biotech that focuses connected the biology of B-cells, a benignant of achromatic humor compartment progressive successful the adaptive immune system. In February, the U.S. Food and Drug Administration approved a TG Therapeutics cause called Ukoniq to dainty certain lymphoma patients.

TG Therapeutics banal climbed sharply this past December, arsenic the institution released affirmative information connected a fig of trials, including a proceedings of its cause umbralisib successful definite leukemia patients. The banal roseate 77.3% successful December of 2020, but is down 27.9% this year.

Analysts stay bullish connected the stock. “We proceed to deliberation that the breadth of TGTX’s pipeline remains underappreciated astatine the existent valuation,” wrote Cantor Fitzgerald expert Alethia Young successful a June 4 note.

The mean people terms connected TG Therapeutics is $75.88, according to FactSet, which implies an 103.3% summation from the stock’s caller terms of $37.32.

Another banal that passed our surface was Vir Biotechnology, the biotech steadfast that changeable to prominence during the Covid-19 pandemic arsenic 1 of the fewer focused connected infectious disease. In May, the FDA authorized a monoclonal antibody therapy jointly developed by Vir and GlaxoSmithKline (GSK) to dainty Covid-19 patients. Unlike different antibody therapies, Vir’s has proven to beryllium effectual against variant strains of the microorganism that origin Covid-19.

Vir shares are up 41.7% truthful acold this year. The institution is besides processing different products, including hepatitis B therapies that are successful Phase 2 trials, and a flu antibody that is successful Phase 1 trials.

Of the 8 analysts tracked by FactSet who support ratings connected Vir, 7 complaint it astatine Buy oregon Overweight, portion 1 rates it astatine Hold. Their mean people terms is $74.29, according to FactSet, which implies a summation of 96% implicit the stock’s caller terms of $37.91.

Also connected our database is Ultragenyx, which develops drugs for uncommon diseases. Its approved therapies see Crysvita, which treats a familial illness called X-linked hypophosphatemia, and Mepsevii, which treats a illness called Mucopolysaccharidosis VII, different uncommon familial condition.

The institution is besides processing cistron therapies for different uncommon diseases. Ultragenyx banal has fallen 37.5% truthful acold this twelvemonth aft a hold successful the restart of its trials of a cistron therapy for Angelman Syndrome, which had been enactment connected objective clasp successful the fall. Analysts, however, spot a buying opportunity.

“We find shares of RARE compelling astatine the existent valuation,” Evercore ISI expert Liisa Bayko wrote successful a enactment upgrading the banal to Outperform from In Line successful aboriginal May.

The mean expert people terms connected Ultragenyx banal is $153.12, according to FactSet, implying a summation of 79.1% implicit the caller stock terms of $85.49.

The last banal to walk our surface was Exelixis, an oncology-focused biotech with a fig of products connected the market, and a pipeline of crab drugs. The banal is down 15.9% truthful acold this year, aft dropping 23.1% connected a azygous time successful precocious June erstwhile a proceedings of its cause cabozantinib successful operation with different cause returned disappointing data.

The mean expert people terms connected the banal is $29.54, according to FactSet, which is 77.2% supra the stock’s caller terms of $16.62. That mean people terms whitethorn not mean much, however, arsenic galore of the people prices acceptable by analysts person not been updated since the late-June drop.

Write to Josh Nathan-Kazis astatine josh.nathan-kazis@barrons.com

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